In this study, we compared the efficacy and safety of a 5-day course of levofloxacin at a dose of 750 mg per day with that of levofloxacin 500 mg per day for
5% vs
Treatment of complicated urinary tract infection and acute pyelonephritis by short-course intravenous levofloxacin (750 mg/day) or conventional intravenous/oral
The clinical response rate was 92% in recipients of the short-course, high-dose levofloxacin regimen and 91% in recipients of the standard regimen; the bacteriological response rates were 93% and 92%
Collection of clinical and microbiologic data
To evaluate the safety and efficacy of a high dose short course of levofloxacin, 780 outpatient adults with clinically and radiologically determined acute bacterial sinusitis were evaluated in a double-blind, randomized, prospective, multicenter study comparing levofloxacin 750 mg by mouth once daily for five days to levofloxacin 500 mg by The 5-day regimen of levofloxacin 750 mg daily is non-inferior to 7-14-day conventional regimen of 500 mg daily in clinical efficacy for treatment of mild to moderate Chinese CAP population and the short course regimen allows the reduction of antimicrobial drug exposure and is well tolerated
Pearls for Practice
High-dose (750 mg) orally administrated levofloxacin over a short 5-day course is a reasonable option for patients eligible for outpatient management
These data demonstrate that 750 mg of levofloxacin per day for 5 days is at least as effective as 500 mg per day for 10 days for treatment of mild-to-severe CAP
The dose is These patients may benefit from a short course (three to five days) of oral decongestants
When dosage in patients with CrCl at least 50 mL/min is 250 mg every 24 hours: CrCl 20 to 49 mL/min: No adjustment recommended
[2,3] To diagnose prostate cancer, a prostate biopsy should be performed
A RCT comparing 5 days of levofloxacin 750 mg daily vs 10 days of levofloxacin 500 mg daily
Drugs
It can weaken your immune system, prolong infection recovery, increase side effects like dizziness and drowsiness, and burden your liver, which processes alcohol and Levofloxacin
4 mg versus 4874